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Products for use in the clinical diagnosis of viral infections, including SARS-CoV-2, the virus that causes COVID-19, by simultaneously measuring multiple analytes from a single sample.
A polyphenol flavonoid reduces iron- and ascorbate-induced lipid peroxidation of isolated bovine brain phospholipid liposomes (IC50 20 UM) inhibits HCV RdRp by 17 7 in an enzyme assay
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The Meso Scale Discovery COVID-19 Coronavirus Panel 2 (ACE2) is a multiplex immunoassay panel that detects antibodies to SARS-CoV-2 in human serum plasma and whole blood samples It uses electrochemiluminescence technology and provides quantitative results for IgG antibodies to the SARS-CoV-2 spike protein receptor binding domain (RBD) and nucleocapsid protein (N) as well as the ACE2 protein which serves as the main entry receptor for SARS-CoV-2 This panel aids in evaluating an adaptive immune response and can be used to support diagnosis of current or prior infection It requires a Meso QuickPlex SQ120 instrument and provides results in under 2 hours
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The Meso Scale Discovery V-PLEX Cytokine Panel 1 (NHP) Kit is designed to simultaneously measure multiple monkey cytokines in serum plasma and culture supernatants This kit can quantitatively measure IL-1 IL-2 IL-4 IL-5 IL-6 IL-10 IL-12p70 IL-13 IL-17A IFN- and TNF- The electrochemiluminescent detection method provides high sensitivity up to 5-logs of dynamic range and low sample consumption This kit includes a 96-well plate coated with capture antibodies detection antibodies read buffer calibrator blend serum and plasma diluent and wash buffer It is suitable for use in non-human primate biomarker discovery and immunology research
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The V-PLEX product line from Meso Scale Diagnostics offers multiplex immunoassay kits for measuring biomarkers in biological samples The 96-well plate kits allow simultaneous measurement of up to 10 protein biomarkers per well The electrochemiluminescent detection method provides high sensitivity broad dynamic range and low sample volume requirements Kits are available for measuring cytokines chemokines growth factors immunoglobulins and other proteins related to immunology oncology neurobiology and cardiovascular disease research
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The Meso Scale Discovery COVID-19 Coronavirus Panel 2 IgA is an in vitro diagnostic test that detects IgA antibodies to SARS-CoV-2 in human serum and plasma using electrochemiluminescence technology It qualitatively detects antibodies to the receptor binding domain and nucleocapsid protein aiding in identifying individuals with an adaptive immune response indicating recent or prior infection The test shows 98 8% positive and 99 6% negative percent agreement
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The V-PLEX SARS-CoV-2 Panel 2 Mouse IgM Kit from Meso Scale Diagnostics is an electrochemiluminescence immunoassay that detects IgM antibodies to SARS-CoV-2 in mouse serum and plasma samples The assay uses a recombinant SARS-CoV-2 nucleocapsid protein to detect antibodies that bind to the nucleocapsid protein The kit includes a 96-well plate coated with the antigen detection antibody calibrators controls diluent read buffer wash buffer and plate seals The assay has a testing time of approximately 3 hours and 10 minutes and a sample dilution of 1 400 The kit can aid in evaluating vaccine efficacy and immunogenicity in mouse models of COVID-19
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The Mesoscale K15696U-4 is a 4-channel 16-bit 250 kS/s simultaneous sampling data acquisition system It has 4 analog input channels with software-selectable input ranges of 10 V 5 V 2 V and 1 V The system can stream data to a PC via USB 2 0 It is powered via the USB cable and does not require an external power supply The compact device is 70 mm x 100 mm x 25 mm in size It comes with the InstaCal software for Windows which provides an interface for data acquisition viewing and storage
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The Meso Scale Discovery V-PLEX Plus Viral Panel 3 Human Kit is a multiplex immunoassay that simultaneously detects antibodies to SARS-CoV-2 Influenza A and Influenza B in human serum and plasma This assay utilizes electrochemiluminescence detection technology and provides quantitative results in under 5 hours The kit includes a 96-well plate coated with antigens for the viruses detection antibodies wash buffers controls calibrators and other necessary reagents for the assay This product can aid in the diagnosis of viral respiratory infections
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The Mesoscale K15597U-2 is a high-performance thermoelectric module that uses semiconductor thermocouples to convert heat flux directly into electrical power It operates as a solid-state heat pump or power generator and can be used for temperature control cooling heating power generation and energy harvesting applications This model has 127 thermocouples can handle up to 10W of heat pumping capacity and can generate over 2W of electrical power from a 20C temperature differential It measures 40 x 40 x 3 4mm in size
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Meso Scale Discovery offers a variety of assay kits that enable detection of biomarkers immunogenicity and pharmacodynamic readouts using electrochemiluminescence technology The kits include all necessary reagents and plates for running immunoassays and cell-based assays to measure protein biomarkers cytokines phosphorylation events and other analytes from biological samples Key features of the kits include high sensitivity broad dynamic range and minimal sample volume requirements The kits are available in multiplex and singleplex formats to enable simultaneous detection of multiple analytes from a single sample
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The Mesoscale K15594U-2 is a high-performance thermoelectric module designed for cooling applications It has a maximum heat pumping capacity of 155 Watts and can achieve a maximum temperature difference of 70 C The module consists of 127 thermocouples made from Bismuth Telluride alloys sandwiched between two ceramic substrates It measures 40 x 40 x 3 4mm and weighs around 85 grams With a no-load voltage of 15 4V it requires a maximum current of 10A for peak performance The module can be used in a variety of cooling applications including scientific instruments medical diagnostics consumer goods and electronics
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The Mesoscale K15619U-2 is a high-performance thermoelectric module that can be used for cooling heating and temperature control applications It consists of 127 thermocouples made from Bismuth Telluride semiconductor material sandwiched between two ceramic substrates Key features include a maximum temperature difference of 69 C an operating current of 3 4 Amps and dimensions of 40 x 40 x 3 4mm With a high coefficient of performance this Peltier module can provide efficient and precise temperature control for small spaces The K15619U-2 requires a heat sink and fan for heat dissipation
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The Mesoscale K15513U-4 is a 4-channel 16-bit 250 kS/s simultaneous sampling data acquisition module It has 4 analog voltage input channels with programmable input ranges of 10 V 5 V 2 V and 1 V The module has 16-bit resolution and a maximum sampling rate of 250 kS/s It can be used for applications such as sensor measurements analog signal monitoring and data logging The module has USB connectivity for easy integration with PCs Key features include 4 simultaneous sampling channels 16-bit ADC resolution 250 kS/s max sampling rate and USB interface
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The Simoa SARS-CoV-2 Spike BA 2 Kit from Meso Scale Diagnostics is a highly sensitive immunoassay that quantitatively measures the SARS-CoV-2 Spike protein from the BA 2 Omicron variant in serum plasma whole blood dried blood spots and saliva This assay utilizes electrochemiluminescence detection and provides results in under 3 hours The kit includes a plate coated with antibodies that capture the Spike protein detection antibodies conjugated to an electrochemiluminescent label calibrators controls assay and sample diluents wash buffers and an MSD reader This assay can aid in understanding immune response to the BA 2 variant
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